Boc-4-amino-3-hydroxybutanoic acid
Boc-4-amino-3-hydroxybutanoic acid
CAS: 69489-07-2
Molecular Formula: C9H17NO5
Boc-4-amino-3-hydroxybutanoic acid - Names and Identifiers
Boc-4-amino-3-hydroxybutanoic acid - Physico-chemical Properties
| Molecular Formula | C9H17NO5 |
| Molar Mass | 219.24 |
| Density | 1.204±0.06 g/cm3(Predicted) |
| Boling Point | 411.8±40.0 °C(Predicted) |
| pKa | 4.30±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Sensitive | Irritant |
| MDL | MFCD02682574 |
Boc-4-amino-3-hydroxybutanoic acid - Risk and Safety
| Hazard Class | IRRITANT |
Boc-4-amino-3-hydroxybutanoic acid - Introduction
Boc-4-Amino-3-hydroxybutyric acid is an organic compound with the chemical formula C10H19NO5. The following is a description of its nature, use, preparation and safety information:
Nature:
Boc-4-amino-3-hydroxybutyric acid is a white to off-white crystalline powder, soluble in some polar solvents such as methanol and ethanol, and slightly soluble in water. Its melting point is about 100-105°C.
Use:
Boc-4-amino -3-hydroxybutyric acid is commonly used as a protecting group in organic synthesis to protect amino and hydroxyl groups. It is also useful as a pharmaceutical intermediate, for example for the synthesis of anticancer drugs.
Preparation Method:
The preparation of Boc-4-amino -3-hydroxybutyric acid usually uses synthetic organic chemistry methods. The specific preparation steps may include the following steps: First, 4-amino-3-hydroxybutyric acid is reacted with tert-butyryl chloride to obtain tert-butyl Boc-4-amino-3-hydroxybutyrate. The tert-butyl ester group is then converted to tert-butanol by acid catalysis. Finally, the pure product was purified by solvent crystallization.
Safety Information:
General laboratory safety measures need to be followed when using and handling Boc-4-amino-3-hydroxybutyric acid. It may be irritating to the eyes, skin and respiratory tract, so avoid contact with eyes and skin and avoid inhaling its dust or mist. Appropriate personal protective equipment, such as lab gloves, goggles, and face shields, should be worn during handling. During storage, the container should be sealed and stored in a dry and cool place to avoid contact with oxidants and high temperatures. In case of accidental exposure or discomfort, medical attention should be sought immediately.
Please note that the above information is for reference only. Please refer to and comply with relevant safety data sheets and laboratory operating specifications for actual operation.
Nature:
Boc-4-amino-3-hydroxybutyric acid is a white to off-white crystalline powder, soluble in some polar solvents such as methanol and ethanol, and slightly soluble in water. Its melting point is about 100-105°C.
Use:
Boc-4-amino -3-hydroxybutyric acid is commonly used as a protecting group in organic synthesis to protect amino and hydroxyl groups. It is also useful as a pharmaceutical intermediate, for example for the synthesis of anticancer drugs.
Preparation Method:
The preparation of Boc-4-amino -3-hydroxybutyric acid usually uses synthetic organic chemistry methods. The specific preparation steps may include the following steps: First, 4-amino-3-hydroxybutyric acid is reacted with tert-butyryl chloride to obtain tert-butyl Boc-4-amino-3-hydroxybutyrate. The tert-butyl ester group is then converted to tert-butanol by acid catalysis. Finally, the pure product was purified by solvent crystallization.
Safety Information:
General laboratory safety measures need to be followed when using and handling Boc-4-amino-3-hydroxybutyric acid. It may be irritating to the eyes, skin and respiratory tract, so avoid contact with eyes and skin and avoid inhaling its dust or mist. Appropriate personal protective equipment, such as lab gloves, goggles, and face shields, should be worn during handling. During storage, the container should be sealed and stored in a dry and cool place to avoid contact with oxidants and high temperatures. In case of accidental exposure or discomfort, medical attention should be sought immediately.
Please note that the above information is for reference only. Please refer to and comply with relevant safety data sheets and laboratory operating specifications for actual operation.
Last Update：2024-04-09 21:01:54
